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IMMUNE SYSTEM

CoV is an enveloped, positive-sense single-stranded RNA (ssRNA) virus belonging to the Coronaviridae family. The CoV family consists of several species and causes upper respiratory tract and gastrointestinal infections in mammals and birds. In humans, it mainly causes common cold, but complications including pneumonia and SARS can occur. (van der Hoek L. Human coronaviruses: What do they cause? Antivir Ther. 2007;12:651–8) The known human CoV (HCoV) includes HCoV-229E, -OC43, -NL63, -HKU1, and the more widely known severe acute respiratory syndrome coronavirus (SARS-CoV) which caused a global threat with high mortality in 2003. (Geller C, Varbanov M, Duval RE. Human coronaviruses:…

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